Buffalo Bills v Jacksonville Jaguars
Nat Coombs presents live coverage of the second game of the 2015 International Series as the Jacksonville Jaguars host fellow AFC Conference side Buffalo Bills at Wembley Stadium.
It will be the third successive year the Jaguars have played in London. They were beaten by the San Francisco 49ers in 2013 and lost to the Dallas Cowboys in 2014. Can the improving Jags enjoy that winning Wembley feeling at the third time of asking? The Bills, four-time Super Bowl runners-up in the early 1990s, will be making their first appearance in the UK.
Studio analysis comes from Mike Carlson and two-time Super Bowl winner Osi Umenyiora.